{"id":6233,"date":"2026-03-04T10:38:37","date_gmt":"2026-03-04T02:38:37","guid":{"rendered":"https:\/\/web.csh.org.tw\/web\/cshmagazine\/?p=6233"},"modified":"2026-03-04T10:38:39","modified_gmt":"2026-03-04T02:38:39","slug":"%e8%aa%8d%e8%ad%98%e5%a4%b1%e6%99%ba%e7%97%87-2","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/cshmagazine\/?p=6233","title":{"rendered":"\u8a8d\u8b58\u5931\u667a\u75c7"},"content":{"rendered":"\n

\u6587\/\u85e5\u5291\u79d1\u5be6\u7fd2\u751f \u5289\u7d39\u6977\u3001\u8521\u6770\u59ae\u3001\u8b1d\u5b9b\u59a4<\/p>\n\n\n\n

\u4e00\u3001\u4f55\u8b02\u5931\u667a\u75c7<\/strong><\/p>\n\n\n\n

\u3000\u3000\u5931\u667a\u75c7\u662f\u4e00\u7a2e\u8166\u90e8\u8a8d\u77e5\u529f\u80fd\u9000\u5316\u7684\u75be\u75c5\u3002\u5b83\u4e26\u975e\u55ae\u4e00\u75be\u75c5\uff0c\u800c\u662f\u4e00\u7fa4\u75c7\u72c0\u7684\u7d44\u5408\uff08\u75c7\u5019\u7fa4\uff09\uff0c\u56b4\u91cd\u7a0b\u5ea6\u8db3\u4ee5\u5f71\u97ff\u500b\u6848\u7684\u4eba\u969b\u95dc\u4fc2\u8207\u65e5\u5e38\u751f\u6d3b\u80fd\u529b\u3002\u4e3b\u8981\u5f71\u97ff\u7684\u4e09\u5927\u5c64\u9762\u5305\u62ec\uff1a\u8a18\u61b6\u529b\u8870\u9000\u3001\u8a8d\u77e5\u529f\u80fd\u4e0b\u964d\uff08\u5982\u8a9e\u8a00\u80fd\u529b\u3001\u7a7a\u9593\u611f\u3001\u5224\u65b7\u529b\u3001\u8a08\u7b97\u529b\u7b49\uff09\u4ee5\u53ca\u500b\u6027\u6216\u884c\u70ba\u7684\u6539\u8b8a\uff08\u5982\u5984\u60f3\u3001\u5e7b\u89ba\uff09\u3002<\/p>\n\n\n\n

\u4e8c\u3001\u5931\u667a\u75c7\u7684\u5206\u985e<\/strong><\/p>\n\n\n\n

\u3000\u3000\u5931\u667a\u75c7\u53ef\u4ee5\u5206\u6210\u4e09\u5927\u985e\uff0c\u4f9d\u53d7\u640d\u8166\u5340\u7684\u4e0d\u540c\uff0c\u75c7\u72c0\u4e5f\u4e0d\u4e00\u6a23\uff1a<\/p>\n\n\n\n

\uff08\u4e00\uff09\u9000\u5316\u6027\u5931\u667a\u75c7<\/p>\n\n\n\n

    \n
  1. \u963f\u8332\u6d77\u9ed8\u75c7\uff08Alzheimer’s disease\uff0cAD\uff09\uff1a\u5931\u667a\u75c7\u6700\u5e38\u898b\u7684\u985e\u578b (\u7d04\u4f54\u6240\u6709\u5931\u667a\u75c760-80%)\uff0c\u4e3b\u8981\u56e0\u03b2-\u985e\u6fb1\u7c89\u86cb\u767d\u5806\u7a4d\uff0c\u5c0e\u81f4\u6d77\u99ac\u8ff4\u9ad8\u5ea6\u840e\u7e2e\u3002\u75c7\u72c0\u901a\u5e38\u5148\u5f9e\u55aa\u5931\u8fd1\u671f\u8a18\u61b6\u958b\u59cb\u3002<\/li>\n\n\n\n
  2. \u8def\u6613\u6c0f\u9ad4\u578b\u5931\u667a\u75c7\uff1a\u5728\u795e\u7d93\u5143\u4e2d\u51fa\u73fe\u7a31\u70ba\u300c\u8def\u6613\u6c0f\u9ad4\u300d\u7684\u86cb\u767d\u8cea\u6c89\u7a4d\uff0c\u5e38\u898b\u8868\u73fe\u70ba\u8996\u5e7b\u89ba\uff0c\u6216\u7761\u7720\u6642\u53ef\u80fd\u51fa\u73fe\u543c\u53eb\u7684\u72c0\u6cc1\u3002<\/li>\n\n\n\n
  3. \u984d\u9873\u8449\u578b\u5931\u667a\u75c7\uff1a\u56e0\u5f71\u97ff\u984d\u8449\u548c\u9873\u8449\uff0c\u5e38\u8868\u73fe\u70ba\u5931\u8a9e\uff08\u8a9e\u8a00\u969c\u7919\uff09\u6216\u500b\u6027\u548c\u884c\u70ba\u4e0a\u7684\u6539\u8b8a\u3002<\/li>\n<\/ol>\n\n\n\n

    \uff08\u4e8c\uff09\u8840\u7ba1\u6027\u5931\u667a\u75c7<\/p>\n\n\n\n

    \u3000\u3000\u7531\u5c0f\u4e2d\u98a8\u6216\u8840\u7ba1\u6027\u4e2d\u98a8\u9020\u6210\u3002\u6cbb\u7642\u91cd\u9ede\u5728\u65bc\u63a7\u5236\u8840\u7ba1\u5371\u96aa\u56e0\u5b50\uff0c\u9810\u9632\u4e2d\u98a8\u518d\u6b21\u767c\u751f\u3002<\/p>\n\n\n\n

    \uff08\u4e09\uff09\u5176\u4ed6\u56e0\u7d20\u5c0e\u81f4\u4e4b\u5931\u667a\u75c7<\/p>\n\n\n\n

    \u3000\u3000\u7531\u7279\u5b9a\u539f\u56e0\u6240\u9020\u6210\uff0c\u7d93\u904e\u6cbb\u7642\u4e4b\u5f8c\u53ef\u80fd\u6709\u6a5f\u6703\u6062\u5fa9\uff0c\u4f8b\u5982\uff1a<\/p>\n\n\n\n

      \n
    1. \u71df\u990a\u5931\u8abf\uff1a\u5982\u7f3a\u4e4f\u7dad\u4ed6\u547dB12\u3001\u8449\u9178\u7b49\u71df\u990a\u7d20\u3002<\/li>\n\n\n\n
    2. \u9871\u5167\u75c5\u7076\uff1a\u5982\u982d\u90e8\u5275\u50b7\u7b49\u3002<\/li>\n<\/ol>\n\n\n
      \n
      \"\"<\/figure><\/div>\n\n\n

      \u4e09\u3001\u5931\u667a\u75c7\u7684\u8a3a\u65b7<\/strong><\/p>\n\n\n\n

      \u3000\u3000\u5931\u667a\u75c7\u7684\u8a3a\u65b7\u4e0d\u80fd\u53ea\u4f9d\u8cf4\u55ae\u4e00\u65b9\u6cd5\uff0c\u901a\u5e38\u9700\u8981\u591a\u9805\u6aa2\u67e5\u548c\u8a55\u4f30\uff1a<\/p>\n\n\n\n

        \n
      1. \u554f\u8a3a\u8207\u795e\u7d93\u5b78\u6aa2\u67e5\uff1a\u8a55\u4f30\u767c\u75c5\u6642\u9593\u3001\u75c7\u72c0\u3001\u75c5\u53f2\uff0c\u4e26\u6aa2\u67e5\u662f\u5426\u6709\u80a2\u9ad4\u7121\u529b\u6216\u5408\u4f75\u5df4\u91d1\u68ee\u6c0f\u75c7\u72c0\u3002<\/li>\n\n\n\n
      2. \u62bd\u8840\u6aa2\u67e5\uff1a\u6392\u9664\u53ef\u80fd\u7684\u53ef\u9006\u6027\u75c5\u56e0\uff0c\u5982\u7dad\u751f\u7d20B12\u7f3a\u4e4f\u3001\u7532\u72c0\u817a\u529f\u80fd\u4f4e\u4e0b\u7b49\u3002<\/li>\n\n\n\n
      3. \u8166\u90e8\u5f71\u50cf\u5b78\uff1a\u900f\u904e\u96fb\u8166\u65b7\u5c64\u6216\u6838\u78c1\u5171\u632f\u8a55\u4f30\u8166\u90e8\u840e\u7e2e\u60c5\u5f62\u3002<\/li>\n\n\n\n
      4. \u8a8d\u77e5\u529f\u80fd\u8a55\u4f30\u91cf\u8868\uff1a\u7528\u65bc\u65e9\u671f\u7be9\u6aa2\uff08\u5982AD8\u3001Mini-Cog\uff09\u3001\u81e8\u5e8a\u4e0a\u6700\u5e38\u4f7f\u7528MMSE\uff0c\u4ee5\u53ca\u7528\u4f86\u8a55\u4f30\u56b4\u91cd\u5ea6\u7684CDR\u91cf\u8868\u3002<\/li>\n<\/ol>\n\n\n\n

        \u56db\u3001\u6cbb\u7642\u85e5\u7269<\/strong><\/p>\n\n\n\n

        1. \u4e59\u91af\u81bd\u9e7c\u916f\u9176\u6291\u5236\u5291\uff08AChEIs\uff09\uff1a<\/p>\n\n\n\n

          \n
        • \u6210\u5206\uff1aDonepezil\uff08\u5982\uff1aAricept\u00ae\u611b\u61b6\u6b23\u53e3\u5d29\u9320\uff09\u3001Galantamine\uff08\u5982\uff1aReminyl\u00ae\u5229\u61b6\u9748\u81a0\u56ca\uff09\u3001Rivastigmine\uff08\u5982\uff1aExelon\u00ae\u61b6\u601d\u80fd\u81a0\u56ca\uff0c\u61b6\u601d\u80fd\u7a7f\u76ae\u8cbc\u7247\uff09\u3002<\/li>\n\n\n\n
        • \u6a5f\u8f49\uff1a\u6291\u5236\u4e59\u91af\u81bd\u9e7c\u7684\u5206\u89e3\uff0c\u589e\u5f37\u795e\u7d93\u8a0a\u865f\u50b3\u905e\uff0c\u5ef6\u7de9\u5fc3\u667a\u9000\u5316\u901f\u5ea6\u3002<\/li>\n\n\n\n
        • \u9069\u61c9\u75c7\uff1a\u7528\u65bc\u8f15\u5ea6\u81f3\u4e2d\u5ea6\u963f\u8332\u6d77\u9ed8\u75c7\uff08Donepezil \u53ef\u7528\u65bc\u4e2d\u91cd\u5ea6\u81f3\u91cd\u5ea6\uff09\u3002<\/li>\n\n\n\n
        • \u5291\u578b\uff1aRivastigmine \u6709\u81a0\u56ca\u3001\u53e3\u670d\u6db2\u5291\u53ca\u7a7f\u76ae\u8cbc\u7247\u5291\u578b\u3002\u8cbc\u7247\u7684\u512a\u9ede\u662f\u8178\u80c3\u9053\u526f\u4f5c\u7528\u8f03\u5c0f\uff0c\u9069\u5408\u541e\u56a5\u56f0\u96e3\u6216\u670d\u85e5\u9806\u5f9e\u6027\u4e0d\u4f73\u8005\u3002\u8cbc\u7247\u9700\u8f2a\u66ff\u9ecf\u8cbc\u90e8\u4f4d\uff0c\u4e14\u4e0d\u53ef\u526a\u88c1\u6216\u6298\u758a\u3002<\/li>\n\n\n\n
        • \u5e38\u898b\u526f\u4f5c\u7528\uff1a\u5641\u5fc3\u3001\u5614\u5410\u3001\u8179\u7009\u3001\u982d\u6688\u548c\u75b2\u5026\uff0c\u901a\u5e38\u6703\u96a8\u6642\u9593\u6539\u5584\u3002<\/li>\n<\/ul>\n\n\n\n

          2. NMDA \u53d7\u9ad4\u62ee\u6297\u5291<\/p>\n\n\n\n

            \n
          • \u6210\u5206\uff1aMemantine\uff08\u5982\uff1aEbixa\u00ae\u61b6\u5fc5\u4f73\u819c\u8863\u9320\u3001Witgen\u00ae\u5a01\u667a\u9320\uff09<\/li>\n\n\n\n
          • \u6a5f\u8f49\uff1a\u7d93\u7531\u5c0dN-Methyl-D-Aspartate\u53d7\u9ad4\u4e4b\u62ee\u6297\u4f5c\u7528\uff0c\u6e1b\u5c11\u904e\u5ea6\u6d3b\u8e8d\u7684\u9ea9\u6c28\u9178(glutamate)\u5c0d\u795e\u7d93\u7d30\u80de\u9020\u6210\u7684\u4e0d\u826f\u5f71\u97ff\uff0c\u5f9e\u800c\u6539\u5584\u75c7\u72c0\u3002<\/li>\n\n\n\n
          • \u9069\u61c9\u75c7\uff1a\u6cbb\u7642\u4e2d\u91cd\u5ea6\u81f3\u91cd\u5ea6\u963f\u8332\u6d77\u9ed8\u75c7\u3002<\/li>\n\n\n\n
          • \u5e38\u898b\u526f\u4f5c\u7528\uff1a\u5305\u542b\u6688\u7729\u3001\u982d\u75db\u3001\u4fbf\u7955\u3002<\/li>\n<\/ul>\n\n\n\n

            3. \u6297 \u03b2 \u985e\u6fb1\u7c89\u86cb\u767d\u55ae\u682a\u6297\u9ad4\u85e5\u7269(\u65b0\u85e5)<\/p>\n\n\n\n

              \n
            • \u6210\u5206\uff1aLecanemab\uff08Leqembi\u00ae\u6a02\u610f\u4fdd\u6fc3\u7e2e\u975c\u8108\u8f38\u6ce8\u6db2\uff09\u3001Donanemab\uff08Kisunla\u00ae\u6b23\u667a\u6a02\u6ce8\u5c04\u5291\uff09\u3002<\/li>\n\n\n\n
            • \u6a5f\u8f49\uff1a\u85c9\u7531\u8207\u985e\u6fb1\u7c89\u86cb\u767d\u7d50\u5408\uff0c\u523a\u6fc0\u514d\u75ab\u7d30\u80de\u6e05\u9664\u5927\u8166\u4e2d\u4e0d\u6b63\u5e38\u7684\u985e\u6fb1\u7c89\u86cb\u767d\u5806\u7a4d\uff0c\u5ef6\u7de9\u65e9\u671f\u75c5\u7a0b\u3002<\/li>\n\n\n\n
            • \u9069\u61c9\u75c7\uff1a\u50c5\u9650\u7528\u65bc\u8a3a\u65b7\u70ba\u8f15\u5ea6\u8a8d\u77e5\u529f\u80fd\u969c\u7919\u548c\u8f15\u5ea6\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u75c5\u4eba\u3002<\/li>\n\n\n\n
            • \u6ce8\u610f\u4e8b\u9805\uff1a\u76ee\u524d\u5065\u4fdd\u5c1a\u672a\u7d66\u4ed8\uff0c\u9700\u8981\u81ea\u8cbb\u4f7f\u7528\u3002\u4f7f\u7528\u524d\u9700\u7d93\u6aa2\u67e5\u8b49\u5be6\u5927\u8166\u6709\u985e\u6fb1\u7c89\u86cb\u767d\u6c89\u7a4d\uff0c\u4e26\u6392\u9664\u91cd\u5927\u51fa\u8840\u98a8\u96aa\u3002\u53ef\u80fd\u51fa\u73fe\u8166\u6c34\u816b\u6216\u5fae\u51fa\u8840\u7684\u526f\u4f5c\u7528\u3002<\/li>\n<\/ul>\n\n\n\n

              \u4e94\u3001\u5931\u667a\u75c7\u7684\u9810\u9632\u8207\u7167\u8b77<\/strong><\/p>\n\n\n\n

              1. \u9810\u9632\u5931\u667a\u75c7<\/p>\n\n\n\n

                \n
              • \u8da8\u5409\uff1a\u591a\u52d5\u8166\u3001\u591a\u904b\u52d5\u3001\u591a\u793e\u6703\u4e92\u52d5\u3001\u5730\u4e2d\u6d77\u578b\u98f2\u98df<\/li>\n\n\n\n
              • \u907f\u51f6\uff1a\u63a7\u5236\u4e09\u9ad8\u3001\u4e0d\u62bd\u83f8\u3001\u9810\u9632\u982d\u90e8\u5916\u50b7\u3001\u9060\u96e2\u6182\u9b31<\/li>\n<\/ul>\n\n\n\n

                2. \u5982\u4f55\u8207\u5931\u667a\u75c7\u60a3\u8005\u6e9d\u901a<\/p>\n\n\n\n

                  \n
                • \u5c0a\u91cd\u75c5\u4eba\uff1a\u7576\u4f5c\u6210\u4eba\u770b\u5f85\uff0c\u4fdd\u6709\u4ed6\u5011\u7684\u81ea\u5c0a\u3002<\/li>\n\n\n\n
                • \u63a5\u7d0d\u611f\u53d7\uff1a\u7406\u89e3\u4ed6\u5011\u8a00\u884c\u80cc\u5f8c\u7684\u60c5\u7dd2\uff0c\u6e1b\u5c11\u8ca0\u9762\u6a19\u7c64\u3002<\/li>\n\n\n\n
                • \u540c\u7406\u5fc3\u7167\u9867\uff1a\u63db\u4f4d\u601d\u8003\uff0c\u5c0b\u627e\u66f4\u5408\u9069\u7684\u4e92\u52d5\u6a21\u5f0f\u3002<\/li>\n\n\n\n
                • \u6e05\u695a\u7c21\u77ed\u6e9d\u901a\uff1a\u4f7f\u7528\u6162\u901f\u3001\u55ae\u4e00\u8a0a\u606f\u6307\u4ee4\uff0c\u4e26\u5584\u7528\u624b\u52e2\u3001\u8868\u60c5\u3001\u773c\u795e\u63a5\u89f8<\/li>\n<\/ul>\n\n\n\n

                  3. \u7167\u9867\u8005\u7684\u81ea\u6211\u8abf\u9069<\/p>\n\n\n\n

                  \u3000\u3000\u7167\u9867\u8005\u5e38\u9762\u81e8\u8eab\u5fc3\u4ff1\u75b2\u3001\u632b\u6298\u611f\u548c\u793e\u4ea4\u5b64\u7acb\u7b49\u56f0\u5883\u3002\u5efa\u8b70\u7167\u9867\u8005\uff1a<\/p>\n\n\n\n

                    \n
                  • \u5b78\u7fd2\u8207\u4ea4\u6d41\uff1a\u8a8d\u8b58\u5931\u667a\u75c7\uff0c\u4e26\u8207\u5176\u4ed6\u7167\u9867\u8005\u6216\u5c08\u5bb6\u4ea4\u6d41\u7d93\u9a57\u3002<\/li>\n\n\n\n
                  • \u7dad\u6301\u898f\u5f8b\u751f\u6d3b\u8207\u5598\u606f\uff1a\u4fdd\u6301\u904b\u52d5\u3001\u7761\u7720\uff0c\u4fdd\u7559\u500b\u4eba\u8208\u8da3\u8207\u793e\u4ea4\uff0c\u4e26\u9069\u6642\u5c0b\u6c42\u5598\u606f\u670d\u52d9\u3002<\/li>\n\n\n\n
                  • \u8abf\u6574\u671f\u671b\uff1a\u7406\u89e3\u9000\u5316\u662f\u75c5\u7a0b\u7684\u4e00\u90e8\u5206\uff0c\u6e1b\u5c11\u904e\u5ea6\u671f\u671b\uff0c\u4e26\u653e\u4e0b\u6127\u759a\u611f\uff0c\u52c7\u65bc\u6c42\u52a9\u3002<\/li>\n\n\n\n
                  • \u5584\u7528\u793e\u6703\u8cc7\u6e90\uff1a\u6d3d\u8a62\u5931\u667a\u75c7\u5354\u6703\uff0c\u4e86\u89e3\u5c45\u5bb6\u3001\u793e\u5340\u6216\u6a5f\u69cb\u5f0f\u670d\u52d9\u7b49\u8cc7\u6e90\u3002<\/li>\n<\/ul>\n\n\n\n

                    \u516d\u3001\u7d50\u8ad6<\/p>\n\n\n\n

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                      \n
                    1. \u53f0\u7063\u5931\u667a\u75c7\u5354\u6703\u3002http:\/\/www.tada2002.org.tw\/<\/li>\n\n\n\n
                    2. \u885b\u751f\u798f\u5229\u90e8\u570b\u6c11\u5065\u5eb7\u7f72\u3002https:\/\/www.hpa.gov.tw\/Home\/Index.aspx<\/li>\n\n\n\n
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