{"id":9426,"date":"2020-07-15T10:33:51","date_gmt":"2020-07-15T02:33:51","guid":{"rendered":"http:\/\/web.csh.org.tw\/web\/csh\/?p=9426"},"modified":"2024-11-13T11:34:40","modified_gmt":"2024-11-13T03:34:40","slug":"quercetin-alleviates-the-accumulation-of-superoxide-in-sodium-iodate-induced-retinal-autophagy-by-regulating-mitochondrial-reactive-oxygen-species-homeostasis-through-enhanced-deacetyl-sod2-via-the-nr","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=9426","title":{"rendered":"Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1\u03b1-Sirt1 Pathway"},"content":{"rendered":"<p><strong>1.<\/strong><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n<p><strong>\u5167\u5bb9\u70ba\u539f\u8457\u7814\u7a76<\/strong><strong>, <\/strong>\u63a2\u8a0eNaIO3\u5f15\u8d77\u5927\u9f20\u8996\u7db2\u819c\u640d\u50b7,\u7d93\u7531\u6c27\u5316\u53ca\u81ea\u566c\u4f5c\u7528\u4e0b,\u518d\u6295\u8207Quercetin\u5f8c\u770b\u5176\u6c27\u5316\u58d3\u529b\u8207\u81ea\u566c\u4f5c\u7528\u4e0b\u7684\u8b8a\u5316,\u6211\u5011\u7684\u7814\u7a76\u767c\u73feindicated that the effects of quercetin on regulating the generation of mtROS were dependent on increased levels of deacetyl-SOD2 through the<br \/>\nNrf2-PGC-1\u03b1-Sirt1 signaling pathway. These results demonstrated that quercetin may have potential therapeutic efficacy for the treatment of AMD through the regulation of mtROS homeostasis.<\/p>\n<p><strong>2.\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n<p>\u7c92\u7dda\u9ad4\u81ea\u55dc\u4f5c\u7528\u5c0d\u65bc\u8996\u7db2\u819c\u6c27\u5316\u58d3\u529b\u5f71\u97ff\u5f88\u591a,\u82e5\u6709\u6297\u6c27\u5316\u7269\u80fd\u6e1b\u7de9\u5176\u6c27\u5316\u58d3\u529b,\u5c0d\u65bc\u75be\u75c5\u9810\u9632\u53ca\u6cbb\u7642\u53ef\u80fd\u6709\u5176\u5e6b\u52a9<!--more--><\/p>\n<p><a href=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2020\/07\/2021-10.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-24604\" src=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2020\/07\/2021-10.jpg\" alt=\"\" width=\"720\" height=\"960\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1.\u7814\u7a76\u7d50\u679c\uff1a \u5167\u5bb9\u70ba\u539f\u8457\u7814\u7a76, \u63a2\u8a0eNaIO3\u5f15\u8d77\u5927\u9f20\u8996\u7db2\u819c\u640d\u50b7,\u7d93\u7531\u6c27\u5316\u53ca\u81ea\u566c\u4f5c\u7528\u4e0b,\u518d\u6295\u8207Quercet [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-9426","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/9426"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9426"}],"version-history":[{"count":2,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/9426\/revisions"}],"predecessor-version":[{"id":24605,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/9426\/revisions\/24605"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9426"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9426"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9426"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}