{"id":5336,"date":"2018-05-17T10:30:18","date_gmt":"2018-05-17T02:30:18","guid":{"rendered":"http:\/\/web.csh.org.tw\/web\/csh\/?p=5336"},"modified":"2018-05-17T10:30:18","modified_gmt":"2018-05-17T02:30:18","slug":"%e7%a0%94%e7%a9%b6%e7%84%a6%e9%bb%9e-6","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=5336","title":{"rendered":"\u7814\u7a76\u7126\u9ede"},"content":{"rendered":"

\u8ad6\u6587\u540d\u7a31<\/strong><\/p>\n

\u4e2d\u6587\uff1a\u863f\u8514\u786b\u7d20\u85c9\u7531\u8abf\u7bc0\u7d44\u7e54\u86cb\u767d\u9176S\u7684\u8868\u73fe\u4f86\u6291\u5236\u53e3\u8154\u764c\u7d30\u80de\u79fb\u52d5<\/strong><\/p>\n

\u82f1\u6587\uff1a\u00a0Sulforaphane suppresses oral cancer cell migration by regulating cathepsin S expression<\/strong><\/p>\n

\u4f5c\u8005\uff1a\u81e8\u5e8a\u7814\u7a76\u4e2d\u5fc3 \u694a\u5609\u6b23 \u7814\u7a76\u54e1<\/strong><\/p>\n

 <\/p>\n\n\n\n
\u672c\u7bc7\u8ad6\u6587\u767c\u8868\u65bcWorld Journal of Gastroenterology<\/strong>\u671f\u520a<\/strong>\u00a02017 November 28; 23(44): 7881-7887<\/strong><\/span>\u5168\u6587\u4e0b\u8f09<\/span><\/strong><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u7814\u7a76\u76ee\u7684\uff1a<\/strong><\/p>\n

Sulforaphane\u662f\u5929\u7136\u7684\u690d\u7269\u5316\u5b78\u5316\u5408\u7269\uff0c\u8403\u53d6\u81ea\u5341\u5b57\u82b1\u79d1\u690d\u7269\uff0c\u4f8b\u5982\uff1a\u7da0\u82b1\u6930\u83dc\u3001\u7518\u85cd\u548c\u82b1\u6930\u83dc\u3002Sulforaphane\u5df2\u8b49\u5be6\u5177\u6709\u8a31\u591a\u751f\u7269\u6d3b\u6027\uff0c\u5305\u542b\u4fdd\u8b77\u795e\u7d93\u3001\u6297\u767c\u708e\u3001\u6297\u8840\u7ba1\u65b0\u751f\u548c\u6297\u764c\u7684\u4f5c\u7528\u3002\u5f88\u591a\u7814\u7a76\u8b49\u660eSulforaphane\u5c0d\u5f88\u591a\u764c\u7d30\u80de\u5177\u6709\u6297\u764c\u7684\u4f5c\u7528\uff0c\u7136\u800cSulforaphane\u5c0d\u53e3\u8154\u764c\u7684\u7814\u7a76\u77e5\u4e4b\u751a\u5c11\uff0c\u56e0\u6b64\uff0c\u672c\u7bc7\u7814\u7a76\u5728\u63a2\u8a0eSulforaphane\u6291\u5236\u53e3\u8154\u764c\u7684\u8f49\u79fb\u80fd\u529b\u53ca\u5176\u5206\u5b50\u6a5f\u5236\u3002<\/p>\n

\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n

\u672c\u7814\u7a76\u767c\u73feSulforaphane\u6703\u6291\u5236\u4eba\u985e\u53e3\u8154\u764c\u7d30\u80de\u682aSCC-9\u548cSCC-14\u7684\u7d30\u80de\u79fb\u52d5\u548c\u4fb5\u8972\u7684\u80fd\u529b\u662f\u900f\u904e\u8abf\u63a7extracellular signal-regulated kinase (ERK)\u8a0a\u606f\u50b3\u905e\u8def\u5f91\u4ee5\u6e1b\u5c11cathepsin S\u7684\u8868\u73fe\u53ca\u589e\u52a0\u4e0b\u6e38microtubule-associated protein 1 light chain 3 (LC3)\u7684\u8868\u73fe\uff0c\u9032\u800c\u8a98\u5c0e\u7d30\u80de\u81ea\u566c(autophage)\u3002<\/p>\n

\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n

\u53e3\u8154\u764c\u662f\u5168\u4e16\u754c\u5e38\u898b\u7684\u60e1\u6027\u816b\u7624\u3002\u5728\u53f0\u7063\u662f\u7b2c\u4e94\u5927\u81f4\u764c\u6b7b\u56e0\uff0c\u4e14\u5176\u767c\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u6709\u9010\u5e74\u589e\u52a0\u7684\u8da8\u52e2\u3002\u53e3\u8154\u764c\u60a3\u8005\u7684\u5e38\u898f\u6cbb\u7642\u5305\u62ec\u55ae\u7368\u6216\u5408\u4f75\u624b\u8853\uff0c\u653e\u7642\u548c\u5316\u7642\u3002\u5118\u7ba1\u53e3\u8154\u764c\u5728\u8a3a\u65b7\u548c\u6cbb\u7642\u65b9\u9762\u5df2\u6709\u5f88\u5927\u7684\u6539\u5584\uff0c\u4f46\u60a3\u8005\u7684\u9810\u5f8c\u548c\u6b7b\u4ea1\u7387\u4ecd\u7136\u5f88\u5dee\uff0c\u5176\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba50\uff05\u3002\u56e0\u6b64\uff0c\u5c0b\u627e\u6709\u6548\u7684\u6cbb\u7642\u7b56\u7565\u4e00\u76f4\u662f\u6700\u91cd\u8981\u7684\u76ee\u6a19\u3002\u672c\u7814\u7a76\u6307\u51faSulforaphane\u80fd\u6291\u5236\u53e3\u8154\u764c\u7d30\u80de\u8f49\u79fb\uff0c\u53ef\u4f5c\u70ba\u7528\u65bc\u6cbb\u7642\u53e3\u8154\u764c\u7684\u6f5b\u5728\u5316\u5b78\u6cbb\u7642\u5291\uff0c\u5176\u4e0b\u6e38\u7684cathepsin S \u548cLC3\u4e5f\u53ef\u4f5c\u70ba\u53e3\u8154\u764c\u6cbb\u7642\u65b0\u7684\u6a19\u9776\uff0c\u63d0\u4f9b\u4e00\u500b\u764c\u75c7\u6cbb\u7642\u65b0\u7684\u7814\u7a76\u65b9\u5411\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u8ad6\u6587\u540d\u7a31 \u4e2d\u6587\uff1a\u863f\u8514\u786b\u7d20\u85c9\u7531\u8abf\u7bc0\u7d44\u7e54\u86cb\u767d\u9176S\u7684\u8868\u73fe\u4f86\u6291\u5236\u53e3\u8154\u764c\u7d30\u80de\u79fb\u52d5 \u82f1\u6587\uff1a\u00a0Sulforaphane su […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5336","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/5336"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5336"}],"version-history":[{"count":1,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/5336\/revisions"}],"predecessor-version":[{"id":5337,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/5336\/revisions\/5337"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}