{"id":3212,"date":"2017-03-15T14:28:23","date_gmt":"2017-03-15T06:28:23","guid":{"rendered":"http:\/\/web.csh.org.tw\/web\/csh\/?p=3212"},"modified":"2024-11-13T11:39:58","modified_gmt":"2024-11-13T03:39:58","slug":"%e8%a4%aa%e9%bb%91%e6%bf%80%e7%b4%a0%e6%8a%91%e5%88%b6%e4%ba%ba%e9%a1%9e%e9%bc%bb%e5%92%bd%e7%99%8c%e7%b4%b0%e8%83%9e%e8%bd%89%e7%a7%bb%e5%8f%8a%e4%be%b5%e8%a5%b2%e6%a9%9f%e5%88%b6%e6%8e%a2%e8%a8%8e","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=3212","title":{"rendered":"\u892a\u9ed1\u6fc0\u7d20\u6291\u5236\u4eba\u985e\u9f3b\u54bd\u764c\u7d30\u80de\u8f49\u79fb\u53ca\u4fb5\u8972\u6a5f\u5236\u63a2\u8a0e"},"content":{"rendered":"<p><strong>1.<\/strong><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n<p>\u672c\u7bc7\u7814\u7a76\u6307\u51fa\uff0c\u5728\u9f3b\u54bd\u764c\u7d30\u80de\u4e2d\uff0c\u892a\u9ed1\u6fc0\u7d20\u80fd\u5920\u900f\u904e\u8abf\u7bc0\u57fa\u8cea\u91d1\u5c6c\u86cb\u767d\u9176 (matrix metalloproteinases\uff0cMMPs)\u4e2d\u7684MMP-9\u4f86\u6291\u5236\u753112-O-tetradecanoylphorbol-13 acetate (TPA)\u6240\u8a98\u767c\u7684\u7d30\u80de\u8f49\u79fb\u3002\u5176\u4e2d\uff0c\u892a\u9ed1\u6fc0\u7d20\u7d93\u7531\u5f71\u97ff\u8f49\u9304\u56e0\u5b50specificity protein-1 (SP-1)\u86cb\u767d\u8868\u73fe\u91cf\uff0c\u9032\u800c\u4f7fMMP-9 mRNA\u8868\u73fe\u91cf\u4e0b\u964d\u3002\u5206\u6790\u5176\u8def\u5f91\u767c\u73fe\uff0c\u892a\u9ed1\u6fc0\u7d20\u900f\u904eMMP-9\u4e0a\u6e38c-Jun N-terminal kinase (JNK)\u8a0a\u606f\u50b3\u905e\u8def\u5f91\uff0c\u5f71\u97ff\u7d30\u80de\u7684\u4fb5\u8972\u53ca\u8f49\u79fb\u3002<\/p>\n<p>2.<strong>\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n<p>\u7d9c\u5408\u4ee5\u4e0a\u7d50\u679c\u8b49\u5be6\uff0c\u892a\u9ed1\u6fc0\u7d20\u900f\u904e\u6291\u5236\u8f49\u9304\u56e0\u5b50SP-1\u8868\u73fe\u91cf\u53caSP-1\u8207MMP-9 DNA\u7684\u7d50\u5408\u80fd\u529b\uff0c\u5f71\u97ff\u7531TPA\u6240\u8a98\u767c\u7684MMP-9\u8868\u73fe\u91cf\uff0c\u4e26\u964d\u4f4e\u9f3b\u54bd\u764c\u7d30\u80de\u682a\u4fb5\u8972\u53ca\u8f49\u79fb\u80fd\u529b\u3002\u7814\u7a76\u9996\u6b21\u767c\u73fe\u892a\u9ed1\u6fc0\u7d20\u5c0d\u9f3b\u54bd\u764c\u7d30\u80de\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u6b64\u4e00\u767c\u73fe\u5c0d\u65bc\u9f3b\u54bd\u764c\u7d30\u80de\u6297\u8f49\u79fb\u7684\u6a5f\u5236\u53c8\u66f4\u52a0\u6df1\u5165\uff0c\u892a\u9ed1\u6fc0\u7d20\u5c0d\u672a\u4f86\u5728\u9f3b\u54bd\u764c\u7684\u6cbb\u7642\u53ef\u80fd\u662f\u4e00\u500b\u6975\u5177\u6f5b\u529b\u7684\u8f14\u52a9\u85e5\u7269\u3002<\/p>\n<p><!--more--><strong><a href=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2017\/03\/2017-16.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-24463 aligncenter\" src=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2017\/03\/2017-16.jpg\" alt=\"\" width=\"720\" height=\"960\"><\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1.\u7814\u7a76\u7d50\u679c\uff1a \u672c\u7bc7\u7814\u7a76\u6307\u51fa\uff0c\u5728\u9f3b\u54bd\u764c\u7d30\u80de\u4e2d\uff0c\u892a\u9ed1\u6fc0\u7d20\u80fd\u5920\u900f\u904e\u8abf\u7bc0\u57fa\u8cea\u91d1\u5c6c\u86cb\u767d\u9176 (matrix metall [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-3212","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3212"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3212"}],"version-history":[{"count":3,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3212\/revisions"}],"predecessor-version":[{"id":24465,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3212\/revisions\/24465"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3212"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3212"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}