{"id":3198,"date":"2017-03-15T14:06:21","date_gmt":"2017-03-15T06:06:21","guid":{"rendered":"http:\/\/web.csh.org.tw\/web\/csh\/?p=3198"},"modified":"2024-11-13T11:40:37","modified_gmt":"2024-11-13T03:40:37","slug":"%e5%88%a9%e7%94%a8exome-sequencing-%e6%8e%a2%e8%a8%8e%e5%8f%a3%e8%85%94%e7%99%8c%e9%ab%94%e7%b4%b0%e8%83%9e%e7%aa%81%e8%ae%8a%e8%88%87%e8%87%a8%e5%ba%8a%e8%a1%a8%e5%be%b5%e7%9a%84%e7%9b%b8%e9%97%9c-2","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=3198","title":{"rendered":"\u5229\u7528Exome sequencing \u63a2\u8a0e\u53e3\u8154\u764c\u9ad4\u7d30\u80de\u7a81\u8b8a\u8207\u81e8\u5e8a\u8868\u5fb5\u7684\u76f8\u95dc\u6027\u63a2\u8a0e"},"content":{"rendered":"<p><strong>1.<\/strong><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n<p>\u672c\u8ad6\u6587\u5229\u7528\u5168\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u5c0b\u627e\u53e3\u8154\u764c\u75c5\u4eba\u5176\u9ad4\u7d30\u80de\u7a81\u8b8a\u57fa\u56e0\u8207\u74b0\u5883\u56e0\u5b50\u4e4b\u95dc\u806f\u3002\u672c\u5be6\u9a57\u5ba4\u5229\u7528120\u7d44\u7f79\u60a3\u53e3\u8154\u764c\u7684\u60a3\u8005\uff0c\u64f7\u53d6\u540c\u4e00\u75c5\u4eba\u7684\u6b63\u5e38\/\u764c\u75c7(normal\/cancer)\u6210\u5c0d\u7684\u7d44\u7e54\uff0c\u9032\u884c\u5168\u57fa\u56e0\u5916\u5b50\u5340\u57df\u7684\u57fa\u56e0\u5e8f\u5217(Whole Exome Sequencing, WES)\u5206\u6790\u3002\u6211\u5011\u7684\u7d50\u679c\u767c\u73fe\u4e00\u4e9b\u982d\u9838\u764c\u9ad4\u7d30\u80de\u7a81\u8b8a\u7684\u5171\u540c\u71b1\u9ede\u57fa\u56e0-\u5982TP53, FAT1, NOTCH1, CASP8, CDKN2A, PIK3CA, HRAS, PCLO, ELAVL1\u53caSVEP1\u5728\u53f0\u7063\u53e3\u8154\u764c\u6709\u8f03\u9ad8\u7684\u7a81\u8b8a\u6bd4\u4f8b\u3002<\/p>\n<p><strong>2.\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n<p>\u5728\u672c\u7814\u7a76\u4e2d\u767c\u73fe\uff0c \u982d\u9838\u764c\u9ad4\u7d30\u80de\u7a81\u8b8a\u7684\u5171\u540c\u71b1\u9ede\u57fa\u56e0\u4e5f\u8a31\u53ef\u4ee5\u7576\u4f5c\u53f0\u7063\u53e3\u8154\u764c\u7684\u6cbb\u7642\u6a19\u7684\u3002<!--more--><\/p>\n<p><strong><a href=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2017\/03\/2017-12.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-24451 aligncenter\" src=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2017\/03\/2017-12.jpg\" alt=\"\" width=\"720\" height=\"960\" \/><\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1.\u7814\u7a76\u7d50\u679c\uff1a \u672c\u8ad6\u6587\u5229\u7528\u5168\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u5c0b\u627e\u53e3\u8154\u764c\u75c5\u4eba\u5176\u9ad4\u7d30\u80de\u7a81\u8b8a\u57fa\u56e0\u8207\u74b0\u5883\u56e0\u5b50\u4e4b\u95dc\u806f\u3002\u672c\u5be6\u9a57\u5ba4\u5229\u7528120\u7d44\u7f79\u60a3 [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-3198","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3198"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3198"}],"version-history":[{"count":4,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3198\/revisions"}],"predecessor-version":[{"id":24616,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/3198\/revisions\/24616"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3198"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3198"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3198"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}