{"id":26997,"date":"2024-11-26T09:51:33","date_gmt":"2024-11-26T01:51:33","guid":{"rendered":"https:\/\/web.csh.org.tw\/web\/csh\/?p=26997"},"modified":"2024-11-26T09:51:34","modified_gmt":"2024-11-26T01:51:34","slug":"association-between-gabapentin-use-and-risk-of-dementia-in-adults-with-chronic-pain-a-nested-case-control-study","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=26997","title":{"rendered":"Association Between Gabapentin Use and Risk of Dementia in Adults with Chronic Pain: A Nested Case-Control Study"},"content":{"rendered":"<ol>\n<li><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/li>\n<\/ol>\n<p>\u5229\u7528\u7e31\u5411\u5065\u5eb7\u4fdd\u96aa\u8cc7\u6599\u5eab\u7684\u8cc7\u6599\u9032\u884c\u5d4c\u5957\u75c5\u4f8b\u5c0d\u7167\u7814\u7a76\u3002\u7814\u7a76\u57fa\u65bc\u53f0\u7063 2000 \u5e74\u81f3 2019 \u5e74\u7684\u7e31\u5411\u5065\u5eb7\u4fdd\u96aa\u8cc7\u6599\u5eab\u3002\u60a3\u8005\uff1a2001 \u5e74\u81f3 2017 \u5e74\u9593\uff0c\u5171\u6709 201,492 \u540d 50 \u6b72\u53ca\u4ee5\u4e0a\u88ab\u8a3a\u65b7\u70ba\u6162\u6027\u75bc\u75db\u7684\u60a3\u8005\u7d0d\u5165\u7814\u7a76\u3002 \u7814\u7a76\u7684\u91cd\u9ede\u662f\u60a3\u6709\u6162\u6027\u75bc\u75db\u7684\u500b\u9ad4\uff0c\u4e0d\u5305\u62ec\u90a3\u4e9b\u5728\u6162\u6027\u75bc\u75db\u8a3a\u65b7\u4e4b\u524d\u6216\u4e4b\u5f8c\u4e00\u5e74\u88ab\u8a3a\u65b7\u51fa\u60a3\u6709\u7661\u5446\u75c7\u7684\u4eba\u3002\u4ecb\u5165\uff1a\u5c0dGabapentin\u8655\u65b9\u53f2\u9032\u884c\u5206\u6790\uff0c\u8003\u616e\u5f9e\u6162\u6027\u75bc\u75db\u8a3a\u65b7\u65e5\u671f\u5230\u5931\u667a\u75c7\u8a3a\u65b7\u65e5\u671f\u6216\u5c0d\u7167\u7d44\u671f\u9593\u7684\u7d2f\u7a4d\u5291\u91cf\u3002\u6578\u64da\u5305\u62ec\u4eba\u53e3\u7d71\u8a08\u3001Gabapentin\u8655\u65b9\u53f2\u548c\u5408\u4f75\u75c7\u3002 \u4f7f\u7528\u908f\u8f2f\u8ff4\u6b78\u4f86\u4f30\u8a08\u5931\u667a\u75c7\u98a8\u96aa\u7684\u6bd4\u503c\u6bd4\u3002\u4e3b\u8981\u7d50\u679c\uff1a\u4f4e\u7d2f\u7a4d\u5291\u91cf\u548c\u9ad8\u7d2f\u7a4d\u5291\u91cf\u7684Gabapentin\u5728\u5931\u667a\u75c7\u98a8\u96aa\u65b9\u9762\u6c92\u6709\u986f\u8457\u5dee\u7570\u3002\u8207Gabapentin\u4f7f\u7528\u76f8\u95dc\u7684\u5931\u667a\u75c7\u98a8\u96aa\u8abf\u6574\u5f8c\u7684\u6bd4\u503c\u6bd4\u70ba 0.91 (95% C.I. 0.83\u20131.01)\uff0c\u986f\u793a\u98a8\u96aa\u6c92\u6709\u986f\u8457\u589e\u52a0\u3002<\/p>\n<ol 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