{"id":26864,"date":"2024-11-25T10:56:41","date_gmt":"2024-11-25T02:56:41","guid":{"rendered":"https:\/\/web.csh.org.tw\/web\/csh\/?p=26864"},"modified":"2024-11-25T10:57:21","modified_gmt":"2024-11-25T02:57:21","slug":"adiponectin-promotes-vegf-expression-in-rheumatoid-arthritis-synovial-fibroblasts-and-induces-endothelial-progenitor-cell-angiogenesis-by-inhibiting-mir-106a-5p","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=26864","title":{"rendered":"Adiponectin Promotes VEGF Expression in Rheumatoid Arthritis Synovial Fibroblasts and Induces Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-106a-5p"},"content":{"rendered":"<p><strong>1.<\/strong><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n<p>\u4eba\u985e MH7A \u6ed1\u819c\u7d30\u80de\u7cfb\u7684\u7814\u7a76\u8868\u660e\uff0c\u806f\u7d20\u5291\u91cf\u548c\u6642\u9593\u4f9d\u8cf4\u6027\u5730\u589e\u52a0\u8840\u7ba1\u5167\u76ae\u751f\u9577\u56e0\u5b50 (VEGF) \u8868\u9054\uff0c\u523a\u6fc0\u5167\u76ae\u7956\u7d30\u80de (EPC) \u7ba1\u5f62\u6210\u548c\u9077\u79fb\u3002 MEK\/ERK \u4fe1\u865f\u4fc3\u9032\u4e86\u9019\u4e9b\u8102\u806f\u7d20\u8a98\u5c0e\u7684\u8840\u7ba1\u751f\u6210\u6d3b\u52d5\u3002\u9ad4\u5167\u5be6\u9a57\u8b49\u5be6\u4e86\u8102\u806f\u7d20\u8a98\u5c0e\u7684 microRNA-106a-5p (miR-106a-5p) \u4e0b\u8abf\u3002\u6291\u5236\u8102\u806f\u7d20\u53ef\u6e1b\u5c11\u81a0\u539f\u6027\u95dc\u7bc0\u708e (CIA) \u5c0f\u9f20\u7684\u95dc\u7bc0\u816b\u8139\u3001\u9aa8\u8cea\u7834\u58de\u548c\u8840\u7ba1\u751f\u6210\u6a19\u8a8c\u7269\u8868\u9054\u3002<\/p>\n<p><strong>2.\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n<p>\u6211\u5011\u7684\u7814\u7a76\u8b49\u660e\u9776\u5411\u8102\u806f\u7d20\u5c0d RA \u60a3\u8005\u4ff1\u6709\u6cbb\u7642\u6f5b\u529b\u3002<!--more--><a href=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2024\/11\/2023-2-28.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-26867\" src=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2024\/11\/2023-2-28.jpg\" alt=\"\" width=\"1240\" height=\"1755\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1.\u7814\u7a76\u7d50\u679c\uff1a \u4eba\u985e MH7A \u6ed1\u819c\u7d30\u80de\u7cfb\u7684\u7814\u7a76\u8868\u660e\uff0c\u806f\u7d20\u5291\u91cf\u548c\u6642\u9593\u4f9d\u8cf4\u6027\u5730\u589e\u52a0\u8840\u7ba1\u5167\u76ae\u751f\u9577\u56e0\u5b50 (VEGF) [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-26864","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26864"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26864"}],"version-history":[{"count":2,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26864\/revisions"}],"predecessor-version":[{"id":26868,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26864\/revisions\/26868"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26864"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26864"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26864"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}