{"id":26489,"date":"2024-11-06T11:08:46","date_gmt":"2024-11-06T03:08:46","guid":{"rendered":"http:\/\/web.csh.org.tw\/web\/csh\/?p=26489"},"modified":"2024-11-13T11:17:55","modified_gmt":"2024-11-13T03:17:55","slug":"%e6%9d%9c%e8%8e%8e%e8%97%bb%e7%9a%84%e5%bf%83%e8%87%9f%e4%bf%9d%e8%ad%b7%e6%98%af%e7%b6%93%e7%94%b1%e6%b8%9b%e5%bc%b1tlr4%e4%bf%a1%e6%81%af%e8%a1%a8%e7%8f%be%e4%bb%a5%e5%b0%8d%e6%8a%97%e5%bf%83","status":"publish","type":"post","link":"https:\/\/web.csh.org.tw\/web\/csh\/?p=26489","title":{"rendered":"\u675c\u838e\u85fb\u7684\u5fc3\u81df\u4fdd\u8b77\u662f\u7d93\u7531\u6e1b\u5f31TLR4\u4fe1\u606f\u8868\u73fe\u4ee5\u5c0d\u6297\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3"},"content":{"rendered":"<p><strong>1.<\/strong><strong>\u7814\u7a76\u7d50\u679c\uff1a<\/strong><\/p>\n<p>\u6211\u5011\u5229\u7528\u5de6\u51a0\u72c0\u52d5\u8108\u7d50\u7d2e\u4e00\u5c0f\u6642\u800c\u5f8c\u518d\u704c\u6ce8\u4e09\u5c0f\u6642\u7814\u7a76\u675c\u838e\u85fb\u5728\u5927\u9f20\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u7684\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\uff0c\u7814\u7a76\u767c\u73fe\u675c\u838e\u85fb\u53ef\u4ee5\u660e\u986f\u6e1b\u5c11\u5fc3\u808c\u6897\u585e\u7684\u9ad4\u7a4d\uff0c\u6b64\u5916\uff0c\u675c\u838e\u85fb\u660e\u986f\u6e1b\u5c11\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u6240\u5f15\u8d77\u7684TLR4\u4ee5\u53caCOX-2\u86cb\u767d\u8cea\u8868\u73fe\u53caSTAT1, JAK2, I\u03baB, NF-\u03baB\u6d3b\u6027\uff0c\u800c\u4e14\u675c\u838e\u85fb\u4ea6\u660e\u986f\u6291\u5236caspase-3\u6d3b\u5316\u53caBeclin-1, p62, LC3-I\/II \u86cb\u767d\u8cea\u8868\u73fe\u3002\u672c\u7814\u7a76\u9996\u5148\u8b49\u5be6\u675c\u838e\u85fb\u5c0d\u6297\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u7684\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\u6a5f\u8f49\uff0c\u7d93\u7531\u6e1b\u5f31TLR4\u8a0a\u606f\u50b3\u905e\u8def\u5f91\uff0c\u85c9\u7531\u6297\u767c\u708e\uff0c\u6297\u7d30\u80de\u51cb\u4ea1\uff0c\u8abf\u63a7\u81ea\u566c\u4f5c\u7528\u5c0d\u6297\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u3002<\/p>\n<p><strong>2.\u7814\u7a76\u8ca2\u737b\u8207\u81e8\u5e8a\u61c9\u7528\uff1a<\/strong><\/p>\n<p>\u675c\u838e\u85fb\u8403\u53d6\u7269\u662f\u4e00\u500b\u5f88\u6709\u6f5b\u529b\u7684\u5fc3\u81df\u4fdd\u8b77\u5291\u3002\u6211\u5011\u7814\u7a76\u7684\u7d50\u679c\u53ef\u4ee5\u63d0\u4f9b\u6709\u50f9\u503c\u7684\u6a5f\u8f49\uff0c\u4e86\u89e3\u675c\u838e\u85fb\u8403\u53d6\u7269\u5728\u5c0d\u6297\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u7684\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\u4e2d\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u6b64\u7814\u7a76\u63d0\u4f9b\u4e00\u500b\u6a21\u5f0f\u53ef\u4ee5\u7be9\u9078\u4fdd\u8b77\u5fc3\u81df\u5c0d\u6297\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u7684\u5929\u7136\u7269\u3002<\/p>\n<p><!--more--><\/p>\n<p><strong><a href=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2024\/11\/2023-1-33.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-26490\" src=\"https:\/\/web.csh.org.tw\/web\/csh\/wp-content\/uploads\/2024\/11\/2023-1-33.jpg\" alt=\"\" width=\"1240\" height=\"1755\" \/><\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1.\u7814\u7a76\u7d50\u679c\uff1a \u6211\u5011\u5229\u7528\u5de6\u51a0\u72c0\u52d5\u8108\u7d50\u7d2e\u4e00\u5c0f\u6642\u800c\u5f8c\u518d\u704c\u6ce8\u4e09\u5c0f\u6642\u7814\u7a76\u675c\u838e\u85fb\u5728\u5927\u9f20\u5fc3\u808c\u7f3a\u8840\u518d\u704c\u6ce8\u50b7\u5bb3\u7684\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\uff0c [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-26489","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26489"}],"collection":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26489"}],"version-history":[{"count":1,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26489\/revisions"}],"predecessor-version":[{"id":26491,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=\/wp\/v2\/posts\/26489\/revisions\/26491"}],"wp:attachment":[{"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.csh.org.tw\/web\/csh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}