{"id":4051,"date":"2026-03-06T11:01:58","date_gmt":"2026-03-06T03:01:58","guid":{"rendered":"https:\/\/web.csh.org.tw\/web\/222040-2\/?page_id=4051"},"modified":"2026-03-06T11:01:58","modified_gmt":"2026-03-06T03:01:58","slug":"%e5%aa%92%e5%90%88%e8%a8%88%e7%95%ab%e4%b8%bb%e6%8c%81%e4%ba%ba-%e9%aa%a8%e7%a7%91-%e5%91%82%e5%85%8b%e4%bf%ae%e4%b8%bb%e6%b2%bb%e9%86%ab%e5%b8%ab","status":"publish","type":"page","link":"https:\/\/web.csh.org.tw\/web\/222040-2\/?page_id=4051","title":{"rendered":"\u5a92\u5408\u8a08\u756b\u4e3b\u6301\u4eba\/\u9aa8\u79d1\/\u5442\u514b\u4fee\u4e3b\u6cbb\u91ab\u5e2b"},"content":{"rendered":"\n
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\u73fe\u8077\uff1a<\/strong><\/td>– \u4e2d\u5c71\u91ab\u5b78\u5927\u5b78\u9644\u8a2d\u91ab\u9662\u9aa8\u79d1\u4e3b\u6cbb\u91ab\u5e2b
– \u4e2d\u5c71\u91ab\u5b78\u5927\u5b78\u904b\u52d5\u91ab\u5b78\u79d1\u4e3b\u4efb
– \u6559\u80b2\u90e8\u90e8\u5b9a\u6559\u6388<\/td><\/tr>
\u5c08\u9577\uff1a<\/strong><\/td>\u95dc\u7bc0\u93e1\u624b\u8853\u3001\u4eba\u5de5\u95dc\u7bc0\u7f6e\u63db\u624b\u8853\u3001\u95dc\u7bc0\u75be\u75c5\u3001\u904b\u52d5\u50b7\u5bb3\u3001\u9aa8\u8cea\u758f\u9b06<\/td><\/tr>
\u8fd1\u4e94\u5e74\u8ad6\u6587\u8457\u4f5c\uff1a<\/strong><\/td>\u2022 Lu KH, Wang SI, Yang SF<\/em>. Real-World Evidence Indicates Romosozumab Use Is Associated with a Greater Reduction in Osteoporotic Fractures Than PTH (1\u201334) Analogs in Women. Biol Sex Differ 2025 Dec (Accepted) (SCI, 2024 IF: 5.1; 12.8%)
\u2022 Chou CH, Hsieh YH, Chen PN, Yang JS, Tang CH, Yang SF, Lu KH<\/em>. Suppression of pentraxin 3 inhibits human osteosarcoma cell metastasis by repressing MAZ through STAT3 pathway. Cancer Cell Int 2025 Oct;25(1):359. doi: 10.1186\/s12935-025-04008-1. (SCI, IF: 6.0; Ranking: 55\/328: 16.6%). (2024)
\u2022 Yang JS, Chou CH, Hsieh YH, Tang CH, Lu KH, Yang SF<\/em>. Carbonic Anhydrase IX Induces Human Osteosarcoma Cell Metastasis by Activating HSPA6 Expression Through the AMPK Signalling Pathway. J Cell Mol Med 2025 Aug;29(15):e70763. doi: 10.1111\/jcmm.70763. (SCI, IF: 4.2; Ranking: 85\/204: 41.4%). (2024)
\u2022 Lu KH, Hsieh YH, Lin RC, Tsai MY, Yang SF<\/em>. Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms. J Pineal Res 2025 Jul;77(4):e70062. doi: 10.1111\/jpi.70062. (SCI, IF: 6.3; Ranking: 24\/193: 12.2%). (2024)
\u2022 Lu KH, Wang SI, Yang SF<\/em>. Denosumab withdrawal increases vertebral fracture and mortality risk compared with zoledronate. Eur J Endocrinol 2025 Mar 3;192(3):180-190. doi: 10.1093\/ejendo\/lvaf013. (SCI, IF: 5.3; Ranking: 27\/186: 14.2%). (2023)
\u2022 Lin YH, Yang JS, Chou CH, Huang TY, Yang SF, Lu KH<\/em>. Curcumin Analog GO-Y030 Triggers JNK and p38 Signalling to Activate Apoptotic Cascades in Human Osteosarcoma Cells. J Cell Mol Med 2025 Feb;29(3):e70383. doi: 10.1111\/jcmm.70383. (4.3; Ranking: 58\/189: 30.4%). (2023)
\u2022 Yang JS, Chou CH, Hsieh YH, Lu PW, Lin YC, Yang SF, Lu KH<\/em>. Morin inhibits osteosarcoma migration and invasion by suppressing urokinase plasminogen activator through a signal transducer and an activator of transcription 3. Environ Toxicol 2024 Apr;39(4):2024-2031. doi: 10.1002\/tox.24100. (SCI, IF: 4.4; Ranking: 18\/106: 16.5%). (2023)
\u2022 Hsieh MH, Hsieh YH, Chou CH, Yang JS, Lu PW, Huang TY, Yang SF, Lu KH<\/em>. Apoptotic effect and cell arrest of deoxyshikonin in human osteosarcoma cells through the p38 pathway. J Cell Mol Med 2023 Jun;27(11):1592-1602. doi: 10.1111\/jcmm.17764. (SCI, IF: 5.3; Ranking: 41\/136: 34.2%). (2022)
\u2022 Lu KH, Lu PW, Lin CW, Lu EW, Yang SF<\/em>. Different molecular weights of hyaluronan research in knee osteoarthritis: A state-of-the-art review. Matrix Biol 2023 Mar;117:46-71. doi: 10.1016\/j.matbio.2023.02.006. (SCI, IF: 10.45; Ranking: 29\/297: 9.76%). (2021)
\u2022 Lu KH, Lu PW, Lu EW, Lin CW, Yang SF<\/em>. Curcumin and its Analogs and Carriers: Potential Therapeutic Strategies for Human Osteosarcoma. Int J Biol Sci 2023 Feb 13;19(4):1241-1265. doi: 10.7150\/ijbs.80590. eCollection 2023. (SCI, IF: 10.75; Ranking: 28\/297: 9.43%). (2021)
\u2022 Lu KH, Lu PW, Lin CW, Yang SF<\/em>. Curcumin in human osteosarcoma: From analogs to carriers. Drug Discov Today 2023 Feb;28(2):103437. doi: 10.1016\/j.drudis.2022.103437. (SCI, IF: 8.369; Ranking: 20\/279: 7.17%). (2021)
\u2022 Lu PW, Chou CH, Yang JS, Hsieh YH, Tsai MY, Lu KH, Yang SF<\/em>. HO-3867 Induces Apoptosis via the JNK Signaling Pathway in Human Osteosarcoma Cells. Pharmaceutics 2022 Jun 13;14(6):1257. doi: 10.3390\/pharmaceutics14061257. (SCI, IF: 6.525; Ranking: 39\/279: 14.0%). (2021)
\u2022 Yeh LT, Lin CW, Lu KH, Hsieh YH, Yeh CB, Yang SF, Yang JS<\/em>. Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. Int J Mol Sci 2022 Jan 1;23(1):484. doi: 10.3390\/ijms23010484. (SCI, IF: 10.45; Ranking: 29\/297: 9.76%). (2021)
\u2022 Lu KH, Lu PW, Lu EWH, Tang CH, Su SH, Lin CW, Yang SF. The potential remedy of melatonin on osteoarthritis. J Pineal Res 2021 Oct;71(3):e12762. doi: 10.1111\/jpi.12762. Epub 2021 Sep 5. PMID: 34435392 (SCI, IF: 13.007; Ranking: 12\/273: 5.21%). (2020)
\u2022 Chou CH, Lu KH, Yang JS, Hsieh YH, Lin CW, Yang SF<\/em>. Dihydromyricetin suppresses cell metastasis in human osteosarcoma through SP-1- and NF-kappaB-modulated urokinase plasminogen activator inhibition. Phytomedicine 2021 Sep:90:153642. doi: 10.1016\/j.phymed.2021.153642. (SCI, IF: 5.340; Ranking: 3\/28: 9.93%). (2020)
\u2022 Lu KH, Yang JS, Hsieh YH, Chu HJ, Chou CH, Lu EW, Lin CW, Yang SF<\/em>. Lipocalin-2 Inhibits Osteosarcoma Cell Metastasis by Suppressing MET Expression via the MEK-ERK Pathway. Cancers (Basel) 2021 Jun 25;13(13):3181. doi: 10.3390\/cancers13133181. PMID: 34202288. (SCI, IF: 6.639; Ranking: 51\/242: 20.87%). (2020)
\u2022 Lu PW, Lin RC, Yang JS, Lu EW, Hsieh YH, Tsai MY, Lu KH, Yang SF<\/em>. GO-Y078, a Curcumin Analog, Induces Both Apoptotic Pathways in Human Osteosarcoma Cells via Activation of JNK and p38 Signaling. Pharmaceuticals (Basel) 2021 May 24;14(6):497. doi: 10.3390\/ph14060497. (SCI, IF: 5.863; Ranking: 38\/276: 13.59%). (2020)
\u2022 Hsieh YH, Hsu WH, Yang SF, Liu CJ, Lu KH, Wang PH, Lin RC*. Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin\/FAK\/Cofilin Axis. Pharmaceuticals (Basel) 2021 Mar 14;14(3):260. doi: 10.3390\/ph14030260. (SCI, IF: 5.863; Ranking: 38\/276: 13.59%). (2020)<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n<\/div>\n\n\n\n

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